Powder formulations
Production methods
- ・We can produce both powders (non-granulated) and granules (granulated). Granulation methods supported include wet granulation (kneading method and fluidized bed granulation) and dry granulation. Therefore, we can granulate ingredients that cannot mix with water.
- ・We can also manufacture portioned products using a four-side seal automatic packaging machine.
- Kneading method
- Fluidized bed granulation
- Dry granulation
Production flow
●Powders
Foreign matter removal
Incoming raw materials are sieved using the Comil (a granulator) to remove foreign particles. Additionally, metallic contaminants such as iron powder originating from raw materials are removed by passing them through a magnet.
Particle sizing
When necessary, particles are classified using a vibrating sieve to adjust to the appropriate powder size for the product.
Packaging
Portioned packaging
・The product is filled and sealed using a four-side seal automatic packaging machine and packed into cartons.
Large-quantity packaging
・The product is filled into aluminum or polyolefin bags, heat-sealed, and packed into cartons.
・Alternatively, it can be filled into polyolefin bottles, capped, and packed into cartons.
●Granules
Foreign matter removal
Incoming raw materials are sieved using the Comil (a granulator) to remove foreign particles. Additionally, they are passed through a magnet to remove metallic contaminants.
Raw material milling
When necessary, raw materials are milled using an impact mill (hammer mill).
Blending
Ingredients are uniformly mixed using a container-type mixer (such as a V-blender or Bohle container mixer).
Granulation and sizing
Wet granulation
Kneading method
- ・Raw materials are kneaded with a liquid binder using a kneader to produce a wet mass.
- ・The wet mass is processed into pellets using an extrusion granulator.
- ・The pellets are resized using a crushing granulator (speed mill) to the appropriate particle size.
Fluidized bed granulation
- ・Raw materials are fluidized and sprayed with a liquid binder in a fluidized bed granulator to form granules.
Dry granulation
Dry granulation
・Raw materials are compressed into flakes using a dry granulator (roller compactor).
・The flakes are resized to the appropriate particle size using an oscillating granulator.
Drying
Wet granulation（kneading and fluidized bed methods）
- ・Granules are dried using a fluidized bed dryer and adjusted to the appropriate moisture content.
Dry granulation
・No drying process is required.
Particle sizing
・When necessary, particles are classified using a vibrating sieve to ensure the appropriate powder size for the product.
Packaging
Portioned packaging
・The product is filled and sealed using a four-side seal automatic packaging machine and packed into cartons.
Bulk packaging
・The product is filled into aluminum or polyolefin bags, heat-sealed, and packed into cartons.
・Alternatively, it is filled into polyolefin bottles, capped, and packed into cartons.
Liquid formulations
- ・We are capable of manufacturing a wide range of products, from pharmaceuticals to food additives, with a focus on alcohol-based disinfectants. Our products meet the diverse needs of medical institutions, educational facilities, offices, and households.
- ・We offer comprehensive support from planning to mass production (ODM), with capabilities ranging from small-lot to large-scale manufacturing.
Semi-solid formulations
- ・We quickly manufacture high-quality formulations such as ointments, creams, and gels.
- ・We support a wide variety of packaging formats and provide one-stop services from planning and manufacturing to filling and packaging.
- ・We flexibly accommodate everything from small-lot to large-scale production.
Solid formulations
- ・Raw material weighing, granulation, drying, mixing, and tablet compression are all performed in environments with controlled cleanliness levels.
- ・Tablet identification can be applied not only by embossing but also by printing.
- ・High-precision cameras are used for tablet inspection to prevent foreign matter contamination.
- ・We support a variety of packaging formats, from PTP sheets to bulk filling.
